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March 21, 2023 9 min read

Are you tired of feeling like no matter what you do, you just can't seem to shed those stubborn extra pounds? Since our team is dealing with hypothyroidism, we understand just how frustrating this struggle can be for those who have the condition. One of the most common symptoms of hypothyroidism is weight gain, and unfortunately, it's not always easy to find an effective solution for it.

If you've been searching for the one treatment that can help you lose weight, you might have heard that Nature Throid, a brand-name of natural desiccated thyroid (NDT) or desiccated thyroid extracts (DTE), is effective for weight loss. But is it really? Here's everything you need to know about weight loss and Nature Throid.

What is Nature Throid?

Nature Throid, sometimes called Nature Thyroid by patients, is a thyroid hormone replacement drug manufactured by RLC Labs. It's made from desiccated porcine thyroid glands (Thyroid USP), so it contains both thyroxine (T4) and triiodothyronine (T3). Due to its source, Nautre Throid also consists of naturally occurring thyroid cofactors in trace amounts, such as T1, T2, calcitonin, and iodine. Moreover, it's hypoallergenic since it contains no artificial colors, flavors, eggs, fish, shellfish, yeast, soy, peanut, corn, rice, or any kind of gluten. It's particularly popular among people who want a natural approach to hypothyroidism treatment.

Since Nature Throid is available in 11 strengths ranging from 1/4 grain (16.25 mg) to 3 grain (195 mg), you have a lot of options to find the right dosage for your specific needs.

What is Nature Throid used for?

Nature Throid is one of the prescription drugs for hypothyroidism. Also known as underactive thyroid, hypothyroidism is a condition in which the thyroid fails to produce enough thyroid hormones for the body to function properly. Some of the most common symptoms of hypothyroidism are weight gain, fatigue, and cold intolerance. Hypothyroidism can be caused by a wide range of conditions, such as Hashimoto's thyroiditis, thyroid gland removal surgery (thyroidectomy), and radioactive iodine ablation.

Nature Throid works by supplying the missing thyroid hormones from your body. Thus, you'll have enough thyroid hormones, and your hypothyroidism symptoms will be gone.

In addition to treating hypothyroidism, Nature Throid is also prescribed to treat or prevent goiter. It's sometimes used to test patients for thyroid disorders like thyroid cancer.

Can Nature Throid help me lose weight?

Yes, Nature Throid can help you lose weight. That is if your weight gain is caused by hypothyroidism.

As a natural desiccated thyroid medication, Nature Throid contains both T3 and T4 thyroid hormones. Compared to the standard treatment for hypothyroidism, levothyroxine, natural desiccated thyroid (NDT) medications like Nature Throid have been associated with more weight loss. In fact, one study found that patients on NDT treatment lost an average of 3 pounds compared to those on levothyroxine.

It's worth noting, however, that individual responses to thyroid medications can vary, and weight loss may not be the primary or guaranteed effect of Nature Throid treatment. Furthermore, there are several factors that can contribute to weight gain other than hypothyroidism itself. For instance, fatigue and joint pain caused by hypothyroidism can make it difficult to exercise regularly, leading to weight gain.

Additionally, it's important to keep in mind that weight loss is not the only factor to consider when choosing a hypothyroidism treatment. Other considerations include symptom relief, hormone levels, and potential side effects. Ultimately, the goal of hypothyroidism treatment is to help restore the body's natural hormone balance and improve overall well-being.

How long does it take to lose weight after taking Nature Throid?

Once you start taking the correct dose of Nature Throid, it typically takes 2 to 3 weeks for your TSH and T4 levels to reach normal levels. At that point, you may start to see weight loss results. Therefore, it's crucial to have regular check-ins with your healthcare provider during the first four weeks of treatment to evaluate and adjust your dosage for optimal results.

In general, weight loss results with Nature Throid might not be sudden or significant. Rather, they may happen gradually over time. So, be patient and stay committed to your treatment plan, and the weight loss results will follow.

Can I use Nature Throid as a weight loss medication?

Thyroid medications are sometimes thought of as a weight loss tool because they can help people with thyroid issues lose weight. However, this has led some to view medications like Nature Throid purely as a weight loss medication, even if they do not have hypothyroidism. Some people with hypothyroidism may even take higher doses of medication, believing that it will result in more weight loss.

But this approach is wrong and potentially dangerous. Taking higher than recommended dosages of thyroid hormone preparations for weight loss can lead to a wide range of problems (more on this below). The FDA has warned against using thyroid replacement therapy for weight loss. It's important to understand that Nature Throid and other thyroid medications are not weight reduction drugs, and expecting them to work like one can be risky.

Why shouldn't I use Nature Throid for weight loss if I don't have hypothyroidism?

Taking Nature Throid when you don't have hypothyroidism, or even when you do but exceed the recommended dosage, can lead to hyperthyroidism. In this condition, the thyroid hormone levels in the blood become excessively high. It could backfire and cause you to gain more weight.

Anxiety, sleeplessness, a fast heart rate, muscle weakness, and heat sensitivity are all indications of an overactive thyroid that can make it difficult to lose weight. Stress and worry alone can trigger binge eating or comfort eating, both of which contribute to extra pounds. Because of this, it's highly unlikely that elevated levels of thyroid hormone or a higher dosage of thyroid medicine will cause significant weight loss or gain.

Moreover, long-term overdosing on thyroid hormone can lead to heart failure and osteoporosis. It may even lead to strokes, seizures, shock, coma, and even death.

Why don't I lose much weight even when I've taken the correct dose of Nature Throid?

While taking the correct dose of Nature Throid is important, there are several other factors that can affect weight loss. These may include not taking the medication as directed or the weight gain being caused by factors unrelated to the lack of thyroid hormone itself but rather due to the other symptoms of hypothyroidism like fatigue and joint pain, which can make it harder for you to live a healthy lifestyle. Here are some strategies that may be helpful in promoting effective weight loss:

Take your Nature-Throid the right way

Make sure to take Nature Throid correctly to maximize its benefits. As per the manufacturer's instructions, take it on an empty stomach in the morning, 30-60 minutes before eating or drinking anything with caffeine, with a full 8 oz glass of water. If you've already eaten, wait at least two hours before taking the medication with water, then wait 30-60 minutes before consuming food or caffeine.

It's important to note that certain medications and supplements may decrease the effectiveness of Nature Throid, so take it at least one hour before any other medication. This will help you avoid any unwanted drug interactions.

To avoid any interference with the absorption of Nature Throid, calcium supplements, iron products, or antacids should be taken at least four hours apart. Some foods, such as walnuts, infant soy formula, cottonseed meal, and high-fiber foods, can also affect the medication's absorption. Consult your doctor if you consume these foods to adjust your dosage if necessary. Always adhere to these guidelines unless otherwise directed by your physician.


Hypothyroidism causes a slowing of the metabolism, which makes it difficult to burn calories at the same rate as when the thyroid is healthy. In comparison to someone with a faster metabolism, you will burn fewer calories doing the same amount of work. Thus, making some basic changes to your diet and taking a closer look at your calorie intake as a whole can be useful.

Keeping track of your calorie intake and making little adjustments may help. Some foods and beverages may have a higher calorie count than you'd expect. Changing your diet to include fewer, different, or none of these may have a significant impact on your weight.

Examples of foods that are high in calories:

  • Sodas a 12 oz. serving of regular Coca-Cola has 140 calories, whereas a 12 oz. serving of Diet Coca-Cola has zero calories. However, if you're trying to improve your diet, you might want to stay away from Diet Coke as well because of the artificial sweeteners it includes.

  • Additives - Ranch and other similar dressings can be deceptively rich in calories while providing few if any, health benefits. Around 145 calories can be found in a single serving of ranch dressing.

  • Sweets - Four Twizzlers are already 133 calories. If you're trying to lose weight, you can make a major difference in your calorie consumption and your weight loss efforts by treating candy as a sometimes food rather than a daily staple.

What to include instead

For a healthier diet and effective weight loss, it's important to focus on whole, unprocessed foods. Instead of reaching for packaged and processed foods, choose fresh, whole foods such as fruits, vegetables, lean meats, and healthy fats. These foods are packed with nutrients and will help to fuel your body and promote weight loss.

If you have a sweet tooth, opt for sweet and ripe fruits instead of sugary snacks or desserts. These fruits will provide you with natural sweetness, fiber, and important vitamins and minerals.

When it comes to meats, choose options that are low in Polyunsaturated Fatty Acids (PUFA), such as beef or lamb. Seafood is also a great option for protein and healthy fats.

To further promote weight loss, avoid starchy foods like pasta and potatoes. Instead, focus on incorporating vegetables and fruit. These foods will provide you with essential nutrients while helping to keep you full and satisfied.

Consult a nutritionist if you need advice on what foods to eat and what diet plans might work best for you.


If you are struggling to lose weight due to hypothyroidism, incorporating cardiovascular exercise into your daily routine can be a game-changer. Not only can exercise aid in weight loss, but it also promotes overall health, boosts energy levels, and enhances mood. Experts recommend engaging in at least an hour of cardiovascular exercise every day to get the most benefit.

Aerobic activities such as running, cycling, and dancing are great options for cardiovascular exercise. These activities increase heart rate and oxygen intake, which helps to burn calories and fat more efficiently. In addition, strength training exercises like weightlifting or bodyweight exercises can also be beneficial for building muscle mass, which can help to further increase metabolism and aid in weight loss.

What are the alternatives to Nature-Throid?

If you're someone with hypothyroidism and are seeking to increase your thyroid function to manage your symptoms, such as weight gain, Nature Throid is a popular option. Unfortunately, this brand is currently unavailable, and it's unclear when it will be back in stock. However, there are alternative options you can explore.

Two other popular prescription medications are Armour Thyroid and WP Thyroid, but they also face availability issues at the moment. It can also be challenging to find a healthcare provider who is willing to prescribe these brands.

Fortunately, VitaliThy, a natural desiccated thyroid you can buy online, offers a convenient solution for those who are unable to obtain Nature Throid or other NDT brands. This all-natural NDT supplement can be purchased online and is free of shellfish, fish, eggs, lactose, and gluten. It's also designed to alleviate hypothyroidism symptoms without exacerbating allergies. With just a few clicks, you can have VitaliThy delivered directly to your home without the need to wait in lines at a pharmacy.

Conclusion: Nature Throid may help people with hypothyroidism lose weight

While Nature Throid can be a helpful medication for weight loss, it is not a magic solution. It is important to remember that even if you are taking Nature Throid, your doctor may recommend additional strategies such as diet and exercise to supplement your weight loss efforts.

It is important to note that using thyroid medication solely for weight loss is not recommended, especially for those without hypothyroidism. This can lead to harmful side effects such as hyperthyroidism, which will require its own treatment.

However, if you want to try Nature Throid for the first time or have been prescribed it and are currently having trouble finding it, there are alternative options available. VitaliThy, a natural desiccated thyroid you can buy online, is one such option. It's free of allergens such as shellfish, fish, and eggs, as well as gluten and lactose. Like Nature Throid, VitaliThy contains both T4 and T3 hormones, making it an effective treatment for hypothyroidism and its symptoms, such as weight gain.

Need more tips? Check out How I Lost Weight with Hypothyroidism.

Wojciech Majda
Wojciech Majda

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