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April 03, 2023 4 min read

It appears that NP Thyroid, a medication many of us have come to rely on, has encountered a setback. Acella Pharmaceuticals, LLC, the manufacturer of NP Thyroid, issued a voluntary nationwide recall in early 2021. The company has announced that all strengths of NP Thyroid are back on the market throughout the United States as of 20 October 2021, but many still find the medication hard to find.

So, what's the deal? Should we hold out hope for NP Thyroid's triumphant return, or is it time to move on to new and exciting options? Let's talk all about it below.

What is NP Thyroid?

If you've been taking natural desiccated thyroid (NDT) medication like NP Thyroid, then you likely know what it is, but let's chat about it anyway.

NP Thyroid is a medication used to treat hypothyroidism or underactive thyroid, a condition in which the thyroid gland doesn't produce enough thyroid hormones. What makes it special is that it's a natural desiccated thyroid medication made from dried porcine thyroid glands. This means that it contains both T3 and T4 hormones, which are the main hormones produced by the human thyroid gland. NP Thyroid also contains other hormones naturally produced by the thyroid, such as T2, T1, and Calcitonin, making it a potent and effective treatment option for many patients with hypothyroidism.

Many people also prefer NDT products like NP Thyroid over other thyroid medications like levothyroxine because it has been associated with weight loss. This is especially beneficial for hypothyroid patients who often struggle with unexplained weight gain and difficulty losing weight.

One grain of NP Thyroid (60 mg of the labeled amount of thyroid) contains 38 mcg T4 and 9 mcg T3. It also contains inactive ingredients, including calcium stearate, dextrose (agglomerated), and mineral oil.

Many people consider NP Thyroid as a more affordable option than Armour Thyroid, another brand name of NDT. Whether it's your go-to medication or you're considering it as an alternative, NP Thyroid is a trusted choice that many have found to be effective.

Why was NP Thyroid recalled?

The recent recall of NP Thyroid has caused understandable concern among patients. On 30 April 2021, Acella Pharmaceuticals took the proactive step of voluntarily recalling certain lots of NP Thyroid® (thyroid tablets, USP) in 100- and 7-count bottles. This recall was initiated due to concerns that certain lots of the medication were sub-potent, meaning that they contained less than the labeled amount of T4 and T3.

Patients who have been taking these sub-potent medications may experience symptoms of hypothyroidism, such as fatigue, constipation, dry skin, hair loss, and more. However, it's important to note that the FDA has not received any reports of adverse events related to the recall.

Certain groups of patients, such as newborn infants and pregnant women, may be at a higher risk of serious injury due to the sub-potent medication. Even a slight variation in the potency of the medication can have serious consequences for these groups, including fetal neural and skeletal development problems, fetal hyperthyroidism, and early miscarriage. Elderly patients and those with underlying cardiac disease may also be at risk of toxic cardiac manifestations of hyperthyroidism. So, it's important to take any potential risks seriously.

It's worth noting that the FDA has classified this recall as a Class II recall, which means that while there is a reasonable risk of serious adverse events or serious injury associated with the use of the affected product, the overall risk is still relatively low.

While the recall is certainly a cause for concern, it's also a positive sign that Acella Pharmaceuticals is taking patient safety seriously by taking this action. Patients who have been affected by the recall should speak with their healthcare provider to discuss alternative treatment options.

To date, Acella has received 43 reports of serious adverse events that could possibly be related to the recall. By acting quickly and responsibly, Acella is demonstrating its commitment to patient safety and ensuring that patients receive the highest quality medications possible.

Is NP Thyroid back on the market?

Yes, Acella Pharmaceuticals, LLC, announced on 20 October 2021 that all strengths of NP Thyroid are available at major wholesale and retail pharmacies throughout the United States.

This news was expected to bring relief to patients who rely on the medication for their thyroid condition. However, despite this announcement, many patients are still struggling to find NP Thyroid.

Patients are facing challenges when trying to locate it in pharmacies. In addition, fewer doctors are willing to prescribe it, further complicating matters for those who depend on it.

What are the alternatives to NP Thyroid?

Patients who struggle to access NP Thyroid are often forced to explore alternative options for their thyroid treatment. While there are several options available, many people in the United States turn to Armour Thyroid as a substitute. However, this brand can be expensive, especially without insurance, and many thyroid doctors are hesitant to prescribe it.

Unfortunately, even patients who prefer pure NDT options like WP Thyroid face difficulty, as it has been recalled. However, there is some good news for those seeking alternative options. You can now buy desiccated thyroid online, like VitaliThy.

VitaliThy is an NDT supplement that contains Thyroid USP, similar to Armour Thyroid, NP Thyroid, and WP Thyroid. The product is categorized as a supplement, not medication, due to differing laws and regulations between Vietnam and the US. VitaliThy adheres to high-quality standards set by the Good Manufacturing Practices of the Vietnamese Ministry of Agriculture, which is known for its stringent guidelines.

Not only does VitaliThy contain T4, T3, T2, T1, and Calcitonin, but it is also free from lactose and gluten and does not contain any artificial coloring, artificial flavoring, eggs, shellfish, or fish in its ingredients. This makes it a viable option for those with dietary restrictions or preferences.


Despite the return of NP Thyroid to the market, many individuals who rely on thyroid replacement therapy to manage their hypothyroidism are still struggling to find it. However, it's important to keep in mind that there are other options available for treating this condition, such as VitaliThy, a natural desiccated thyroid you can buy online. With the high-quality standards set by the Good Manufacturing Practices of the Vietnamese Ministry of Agriculture, VitaliThy is a safe and effective alternative for individuals experiencing difficulty accessing NP Thyroid.

Wojciech Majda
Wojciech Majda

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